Progress in the Synthesis of 5-Aminothiazole Derivatives

Synthesis and antifungal activity of benzimidazole, benzotriazole and aminothiazole derivatives

In recent years, the use of antifungal drugs in human medicine has increased, especially with the advent of AIDS epidemic. Efforts have focused on the development of new, less toxic and more efficacious antifungal drugs with novel mechanism of action. The purpose of this study was to synthesize of some new benzimidazole, benzotriazole and aminothiazole derivatives and to evaluate their activity...

An efficient one-pot synthesis of 2-aminothiazole derivatives

A highly efficient, rapid and catalyst free protocol has been developed for the synthesis of 2-aminothiazoles in tetrahydrofuran (THF). Reaction was carried out at room temperature and the products were obtained in high yields without further purification.

comparison of catalytic activity of heteropoly compounds in the synthesis of bis(indolyl)alkanes.

heteropoly acids (hpa) and their salts have advantages as catalysts which make them both economically and environmentally attractive, strong br?nsted acidity, exhibiting fast reversible multi-electron redox transformations under rather mild conditions, very high solubility in polar solvents, fairly high thermal stability in the solid states, and efficient oxidizing ability, so that they are imp...

synthesis and antifungal activity of benzimidazole, benzotriazole and aminothiazole derivatives

Synthesis and Evaluation of Aminothiazole-Paeonol Derivatives as Potential Anticancer Agents.

In this study, novel aminothiazole-paeonol derivatives were synthesized and characterized using ¹H-NMR, (13)C-NMR, IR, mass spectroscopy, and high performance liquid chromatography. All the new synthesized compounds were evaluated according to their anticancer effect on seven cancer cell lines. The experimental results indicated that these compounds possess high anticancer potential regarding h...